IGF-1 LR3, also known as Long R3 IGF-1, is a modified analogue of Insulin-Like Growth Factor-1 (IGF-1) developed primarily for laboratory and biochemical research.

IGF-1 is a naturally occurring peptide hormone involved in cell growth, development, metabolism and tissue maintenance. It is closely associated with growth hormone (GH) signalling and plays an important role in many tissues throughout the body.

IGF-1 LR3 was engineered to modify the biological characteristics of natural IGF-1, particularly its interaction with IGF-binding proteins.

How IGF-1 LR3 Works

IGF-1 LR3 primarily interacts with the IGF-1 receptor (IGF-1R).

Activation of this receptor can influence several intracellular signalling pathways, including the PI3K/Akt/mTOR and MAPK pathways.

These signalling systems are involved in processes such as:

• Cell growth and proliferation
• Protein synthesis
• Cellular survival
• Glucose and nutrient metabolism
• Tissue development and repair

Because these pathways regulate fundamental cellular processes, IGF-1 signalling is extensively studied across endocrinology, metabolism and cell biology.