VIP
$140,00
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Vasoactive intestinal peptide (VIP) is a 28-amino-acid neuropeptide acting as a potent vasodilator, neurotransmitter, and immunomodulator found throughout the central/peripheral nervous systems and gastrointestinal tract.
It regulates smooth muscle relaxation, epithelial secretion, and blood flow, with emerging therapeutic roles in treating pulmonary hypertension, erectile dysfunction, and inflammatory conditions.
Research use only. Not for human or veterinary use.
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Key Aspects of VIP Peptide:
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- Functions: As a neurotransmitter and neurohormone, VIP regulates intestinal secretion, relaxes airway smooth muscle, and acts as a vasodilator.
- Immune Regulation: VIP is heavily involved in controlling innate and adaptive immune responses, exerting anti-inflammatory effects
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- Clinical Applications: VIP has been tested for treating erectile dysfunction (e.g., Invicorp), pulmonary hypertension, and chronic sarcoidosis.
- Pathology Link: Elevated VIP levels in the blood are used to diagnose VIPoma, a rare type of neuroendocrine tumour usually located in the pancreas.
- Mechanism: It acts via G protein-coupled receptors (VPAC1, VPAC2, and PAC1) to modulate cellular activities.
Clinical Significance & Research
Respiratory Role: VIP is an important inhibitory transmitter in the lung that controls airway tone and has potential as an inhaled agonist for treating asthma.
- Neuroprotection: Studies are exploring the role of VIP and its receptors in treating neurological disorders like Alzheimer’s, Parkinson’s, and Autism Spectrum Disorders.
- Inflammatory Disease: VIP helps suppress autoimmune disease progression in animal models by inducing regulatory T cells.
- Diagnostic Utility: Testing for vasoactive intestinal peptide is used to investigate persistent, severe watery diarrhea.
- Reconstitution in Bac Water: 2ml of Bac Water, starting dose, 10 units sub injection.
Research Use Only: Not for human or veterinary use.
| Strength | 5 mg, 10 mg |
|---|---|
| Pack size | 1 vial, 2 vials, 3 vials |
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